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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBR1 All Species: 12.42
Human Site: T457 Identified Species: 27.33
UniProt: Q16650 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16650 NP_006584.1 682 74053 T457 G A G P G P G T D R S V P H T
Chimpanzee Pan troglodytes XP_526157 702 74704 S470 E N D R L T P S P T D S P R S
Rhesus Macaque Macaca mulatta XP_001093085 737 80029 N480 T Q L K I D H N P F A K G F R
Dog Lupus familis XP_545492 682 73929 T457 G A G P G P G T D R S V P H T
Cat Felis silvestris
Mouse Mus musculus Q64336 681 73923 T457 G A G P G P G T D R S V P H T
Rat Rattus norvegicus Q5I2P1 517 57726 S297 Y Q C E N G V S G P S Q D L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514679 386 42515 V166 G F R E N Y D V M F S A P A E
Chicken Gallus gallus Q9PWE8 521 58384 T300 C E N G V S S T S Q D L L P P
Frog Xenopus laevis P79944 692 75925 S452 Y D S M Y T A S E S D R L T P
Zebra Danio Brachydanio rerio Q9IAK8 492 55218 S270 V R Q R V G S S Q S P F S G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791266 946 105128 K700 D S S T S S P K P F P I P V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49 46.8 99.2 N.A. 99.1 24.6 N.A. 30.3 24.4 50 25.5 N.A. N.A. N.A. N.A. 26.7
Protein Similarity: 100 64 60.5 99.5 N.A. 99.2 37.2 N.A. 38.1 36.5 65 37.5 N.A. N.A. N.A. N.A. 40.7
P-Site Identity: 100 6.6 0 100 N.A. 100 6.6 N.A. 20 6.6 0 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 6.6 100 N.A. 100 13.3 N.A. 20 20 13.3 6.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 0 0 0 0 10 0 0 0 10 10 0 10 0 % A
% Cys: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 10 0 0 10 10 0 28 0 28 0 10 0 10 % D
% Glu: 10 10 0 19 0 0 0 0 10 0 0 0 0 0 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 28 0 10 0 10 0 % F
% Gly: 37 0 28 10 28 19 28 0 10 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 28 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 10 0 0 0 10 0 0 0 % K
% Leu: 0 0 10 0 10 0 0 0 0 0 0 10 19 10 10 % L
% Met: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 19 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 28 0 28 19 0 28 10 19 0 55 10 28 % P
% Gln: 0 19 10 0 0 0 0 0 10 10 0 10 0 0 0 % Q
% Arg: 0 10 10 19 0 0 0 0 0 28 0 10 0 10 10 % R
% Ser: 0 10 19 0 10 19 19 37 10 19 46 10 10 0 10 % S
% Thr: 10 0 0 10 0 19 0 37 0 10 0 0 0 10 28 % T
% Val: 10 0 0 0 19 0 10 10 0 0 0 28 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _